OXIDATIVE STRESS & MACULAR DEGENERATION

Oxidative Stress & Cataracts
April 14, 2018
Mechanism of Injury to the Retina
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In India, age related macular degeneration (ARMD) is the leading cause of blindness in people more than 60 years old. For those who are not familiar with this disease, it is a decay of a critical part of the retina called the macula. This where the greatest concentration of photoreceptors is located and is the area responsible for central vision. When this area of eye begins to decline, we essentially lose central vision, our most important aspect of sight. If an individual with ARMD were to look right at you, he would not be able to see your face but could see things around you. In other words peripheral vision remains intact Macular degeneration presents itself in two different form- Wet & Dry. More than 90% cases involve the dry form, in which the central vision gradually reduces & may progress to the wet form about 10% of the time. No proven treatment for the dry form of macular degeneration currently exists. The wet form causes more rapid reduction in central vision, the development of new vessels, and possible vessel leakage. The wet form of macular degeneration is potentially treatable via laser photocoagulation. This treatment attempts to slow the new vessel production, which causes swelling (edema) and leakage or bleeding into the retina and to stop the bleeding this leakage may cause blindness. Blindness usually still follows rather quickly, however.