Those who have low levels of Vitamin-C have an increased risk of developing ARMD. Vitamin C is highly concentrated in the fluid within the eye (aqueous humor) and is very important antioxidant for the retina. Studies indicate that supplementation with Vitamin-C can slow down the progression of ARMD. Vitamin C also has the ability to regenerate both Vitamin-E and the potent intracellular antioxidant glutathione.
ARMD patients have low levels of Vitamin-E in the area of macula, where high energy light produces excessive free radicals that damage the photoreceptors. Even though. Vitamin E is not the most important antioxidant within the eye, it is still a critical player. When a patient takes Vitamin-E in supplementation, he may provide protection against the development of ARMD.
Coenzyme Q10 have been discussed in some of our previous blogs. Coenzyme Q10 is a potent antioxidant that is fat soluble. This nutrient has been found to be a great protector of fat soluble. This nutrient has been found to be a great protector of fats throughout the body. The retina of the eye, which is made up in large part by fat, is no exception. Patients with ARMD shown significantly depleted amount of Co Q10. Those patients with normal levels of Co Q10 have greater capacity to resist oxidative damage that excessive free radicals cause. Co Q10 is new in the study of ARMD and its effects are promising.
It is a very potent antioxidant found within every cell in the body. It is especially critical within the lens of the eye as well as the pigment and photoreceptor cells of the retina. Clinical studies have shown that as we age, the level of glutathione declines. This fact is needed to consider in relation to the increase of diseases in the eye as we age. Several studies have looked at trying to increase the level of this crucial antioxidant within the lens and retina of the eye.
Among researchers, it is a well known fact that our body absorbs oral glutathione poorly; raising cells levels of glutathione through this method is next to impossible. The best way to increase intra cellular glutathione levels is to provide nutrients that the body needs to manufacture its own glutathione. It is one of the natural antioxidant defense systems that the body creates. The nutrients needed for the body to make its own effective, natural defense are selenium, Vitamin B-6, N-acetyl-L-Cysteine and Niacin.
As we learn more about cellular nutrition, we will begin to realize the importance of providing all of these nutrients to the cell. In this case alpha-lipoic acid and Vitamin C are also critical because they both have the ability to generate glutathione. Since it is difficult to increase the levels of glutathione within the cell, these nutrients should also be present in supplementation so that the glutathione can be used again & again. Researchers have demonstrated that when the photoreceptor and retinal pigmented cells have optional levels of antioxidants present, they are much better able to protect these cells from oxidative damage. The lens of the eye is also better protected against oxidative damage when glutathione levels are higher.
ZINC & SELENIUM
Do you know that zinc & Selenium are important minerals our antioxidant system needs. Zinc is critical for the function of our catalase antioxidant defense system and selenium is necessary to the glutathione peroxides system. Both of these antioxidants defense system are essential in the battle against free radicals produced in the eye. If these two minerals are not available in adequate amounts, the two defense systems simply cannot perform at their optimal level. Several studies now show that when these minerals are supplemented, especially zinc, ARMD can actually be stabilized and improved.