Studies show that grape seed extract crosses the blood brain barrier quite readily. It is an exceptionally potent antioxidant and the mere fact that high concentrations can be obtained in the fluid and cells of the brain and nerve tissue makes it an ideal antioxidant for the brain. My experience shows that this nutrient is a major player in the amazing results. I have seen among patients who are suffering from neurodegenerative diseases. I believe it is by far the most important optimizer in these diseases. It is obviously one of the antioxidants that researchers should use further in studies involving these diseases.